Tag: Glenmark Pharmaceuticals Ltd.

Health

Glenmark launches SUTIB (Sunitinib) –priced 96% lower than the innovator brand

Feb 17, 2021 by Neel Achary 0 Comments #Glenmark Pharmaceuticals Ltd., #Group Vice President & Business Head, #India Formulations., #Mr. Alok Malik

Oral capsules, highly affordable at Rs. 7000 (50 mg), Rs. 3600 (25 mg) and Rs. 1840 (12.5 mg) per month
SUTIB (Sunitinib) is one of the “gold-standard” first-line treatment options for kidney cancer
SUTIB is the generic version of US FDA approved Sunitinib

Glenmark Pharmaceuticals, a research-led, global integrated pharmaceutical company, today launched SUTIB, the generic version of Sunitiniboral capsules to treat kidney cancer in India. The drug is launched at an MRP that is approx.96% lower than the MRP compared to the innovator brand, priced at Rs. 7000 (50 mg), Rs. 3600 (25 mg) and Rs. 1840 (12.5 mg) per month. Sunitinib is also approved by the US Food and Drug Administration (US FDA).
Kidney cancer (renal cell carcinoma) is a disease of uncontrolled cell growth in the lining of small tubes in the kidney. In the past decade, advances in research and drug development have begun to shift the paradigm of this disease. Sunitinib is an oral multi-kinase inhibitor (MKI), works by blocking several enzymes that promote cell growth. It is useful for the treatment of certain patients with gastrointestinal stromal tumors and advanced renal cell carcinoma. It is also approved for patients with a certain type of Pancreatic Neuroendocrine Tumours.
According to a Globocan 2020 report, there are close to 40,000 patients with renal cancer in India. For over a decade, Sunitinib has been well recognized as one of the “gold-standard” of care in cases of fast-spreading (metastatic) renal cancer. Research shows that Sunitinibalone has helped reduce the risk of progression of renal cancer by 58%.3.

Commenting on the launch, Mr. Alok Malik, Group Vice President & Business Head, India Formulations, said, “Oncology is an important focus area for Glenmark. We recognize that advanced kidney cancer is a complex disease and patients in India are faced with limited treatment options. Glenmark is committed to bringing targeted and effective medicines at an affordable costto physicians and their patients.”

About Glenmark Pharmaceuticals Ltd
Glenmark Pharmaceuticals Ltd. (GPL) is a global research-led pharmaceutical company with a presence across Generics, Specialty, and OTC business with operations in over 50 countries. Glenmark’s key therapy focus areas globally are respiratory, dermatology, and oncology. It is ranked among the top 80 Pharma & Biotech companies of the world in terms of revenue (SCRIP 100 Rankings published in the year 2019). The company has been listed in the Dow Jones Sustainability Index (DJSI), under the category of emerging markets for the third consecutive year in a row. DJSI is one of the world’s most respected and widely accepted sustainability benchmarks globally with only the top-ranked companies in terms of Corporate Sustainability within each industry are featured in the index. For more information, visit www.glenmarkpharma.com

Business World

Glenmark introduces higher strength (400 mg) of FabiFlu(R) to reduce the pill burden of COVID-19 treatment

Aug 7, 2020 by Gouri Achary 0 Comments #400 mg version of oral antiviral FabiFlu®, #Clinical Development, #Dr. Monika Tandon, #for the treatment of mild to moderate COVID-19 in India., #Glenmark Pharmaceuticals, #Glenmark Pharmaceuticals Ltd., #Global Specialty/Branded Portfolio, #Post Marketing Surveillance (PMS) study on FabiFlu®, #Vice President & Head

Glenmark Pharmaceuticals, a research-led, integrated global pharmaceutical company, today announced that it will introduce a 400 mg version of oral antiviral FabiFlu®, for the treatment of mild to moderate COVID-19 in India. The higher strength will improve patient compliance and experience, by effectively reducing the number of tablets that patients require per day.

A higher pill burden has been associated with lower adherence to therapy, the latter affecting viral suppression and overall treatment outcomes. Also reducing the pill burden has been a demand from doctors and patients to enable adherence. The 200 mg dosage of FabiFlu® required patients to take 18 tablets on Day 1 (nine in the morning and nine in the evening), followed by 8 tablets each day thereafter for a maximum of 14 days. With the new 400 mg version, patients will now have a more relaxed dosage regimen, with 9 tablets required on Day 1( 4.5 in the morning and 4.5 in the evening), and thereafter 2 tablets twice a day from Day 2 till the end of the course.

Explaining the significance of this development, Dr. Monika Tandon, Vice President & Head, Clinical Development, Global Specialty/Branded Portfolio, Glenmark Pharmaceuticals Ltd., said, “Being the first company to launch Favipiravir in India, we continue to innovate and seek new treatment options for Covid-19 patients. Introducing this higher strength of FabiFlu® is in line with these efforts to ensure a smoother experience for patients, by reducing their daily pill burden.”

“The 200 mg dosage of FabiFlu® was developed in line with global formulations of the drug Favipiravir, which had similar strength. The 400 mg version is a result of Glenmark’s own R&D efforts to improve the treatment experience for patients in India,” she added.

Glenmark has also commenced a Post Marketing Surveillance (PMS) study on FabiFlu® to closely monitor the efficacy and safety of the drug in a large pool of patients prescribed with the oral antiviralFavipiravir, as part of an open-label, multicenter, single-arm study. Glenmark is also conducting another Phase 3 clinical trial to evaluate the efficacy of two antivirals drugs Favipiravir and Umifenovir as a combination therapy in moderate hospitalized adult COVID-19 patients in India. The combination study which is called the FAITH trial is looking to enrol 158 hospitalized patients of moderate COVID-19 in India. Early treatment with combination therapy will be evaluated for safety and efficacy as it is emerging as an effective approach in shortening duration of virus shedding, facilitating early clinical cure and discharge of patients.